Lantern Grants

Leveraging functional genomics to reveal novel targets for cancer treatment

Funder
European Commission · Horizon Europe · EU Missions
Award amount
€7,000,000 – €8,000,000
Deadline
September 16, 2027
Eligible countries
European Union, United Kingdom, Norway, Iceland, Switzerland, Israel, Global

Summary

Forthcoming EU call topic HORIZON-MISS-2027-02-CANCER-01 · HORIZON Research and Innovation Actions. Part of call HORIZON-MISS-2027-02: Supporting the implementation of the Cancer Mission. Opens 2027-02-10; next deadline 2027-09-16. Topic page: https://ec.europa.eu/info/funding-tenders/opportunities/portal/screen/opportunities/topic-details/HORIZON-MISS-2027-02-CANCER-01

Expected Outcome: Proposals under this topic should aim to deliver results that are directed and tailored towards and contribute to all of the following expected outcomes: - Researchers and health professionals gain a deeper understanding of the functional effects of tumour heterogeneity during cancer initiation and progression, supporting the identification of more precise and novel therapeutic targets. - Researchers, health professionals and innovators benefit from improved knowledge and tools to support the discovery and development of next generation genomically-informed cancer treatments. - Researchers, innovators, and professionals across disciplines and sectors contribute to the UNCAN.eu research data platform by ensuring data interoperability, and enabling sustainable access to newly developed digital tools and models for the analysis and management of multimodal clinical data.

Scope: The proposed topic will contribute to the EU Cancer Mission objective of improving the understanding of cancer initiation and progression. Of particular interest for this topic are paediatric and adolescent cancers[1] , cancers with limited treatment options, refractory cancers, rare cancers or cancer types with low five-year survival rates. Proposals may include the design of exploratory mechanistic studies using longitudinal patient bio-samples, clinical proof-of-concept studies and/or observational and translational studies involving newly collected or existing data, as appropriate. Applicants are encouraged to leverage technological advances in functional genomics[2] and structural biology including but…

Summary as listed by the funder. Always read the full announcement for eligibility, limits and how to apply.

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What European Union reviewers look for

  • Most Horizon Europe calls score three criteria (the ERC uses excellence alone). Excellence: clarity and ambition of the objectives, and the soundness of the methodology.
  • Impact: credible pathways to the expected outcomes, and measures to communicate and exploit results.
  • Quality and efficiency of implementation: the work plan, resources and the consortium's capacity.

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