Implementation and Evaluation of Databases to Examine AIDS

Forecasted opportunity (not yet open for applications; expected to be posted around 2027-02-18; estimated application due date 2027-05-27). The National Institute of Allergy and Infectious Diseases (NIAID), with partnering National Institutes of Health Institutes, Centers, and Offices, seeks to advance its mission through continued support for the Implementation and Evaluation of Databases to Examine AIDS Consortium. This research network integrates clinical, epidemiologic, genomic, and contextual real-world data through harmonized data standards and interoperable data systems to generate evidence, perform data-driven research, and advance implementation science. Regional Cohort Centers collaborate across scientific working groups to investigate research priorities and develop innovative analytic methods. The consortium will apply cutting-edge data science approaches and incorporate emerging artificial intelligence technologies through scalable tools, computational models, and workflows to support data sharing, re-use, and reproducibility. The consortium supports studies of HIV morbidity, mortality, comorbidities, and multidimensional risk factors for HIV. As a platform for implementation science, the consortium evaluates strategies to improve HIV prevention, treatment, and care, contributing to the goals of the U.S. Ending the HIV Epidemic initiative. Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.