HIV/AIDS Clinical Trials Network Clinical Trials Units

Forecasted opportunity (not yet open for applications; expected to be posted around 2026-08-25; estimated application due date 2027-01-22). The National Institute of Allergy and Infectious Diseases (NIAID) seeks to advance the National Institutes of Health (NIH) mission by supporting four Clinical Trials Networks (CTNs) each comprised of a Leadership and Operations Center, Statistical and Data Management Center, and Laboratory Center working with Clinical Trials Units (CTUs), to advance prevention and treatment research on HIV and HIV-associated diseases. CTNs will conduct randomized controlled clinical studies at CTUs testing innovative strategies and conduct implementation research targeted to end the HIV epidemic. This NOFO will solicit applications for CTUs providing scientific expertise to conduct these clinical trials and implementation research studies. Each CTU will include an administrative hub and domestic and/or international Clinical Research Sites to promote efficient utilization of resources and infrastructure. CTUs conduct multiple clinical studies, from more than one CTN, and can access, recruit, and retain relevant study participants. International studies produce crucial findings significantly benefiting Americans with or at-risk of HIV or HIV-related diseases.Grant authorities that allow NIAID to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.