Clinical Trials and Ancillary Studies Conducted within NIH-Funded Clinical Trial Research Networks (UG3/UH3 - Clinical Trial Required)

Forecasted opportunity (not yet open for applications; expected to be posted around 2026-10-10; estimated application due date 2026-11-10). The National Institute of Neurological Disorders and Stroke (NINDS), in conjunction with additional Institutes/Centers (ICs)at the National Institutes of Health seek to support projects proposing Clinical Trials and Ancillary Studies that are conducted within NIH-Funded Clinical Trial Research Networks.The program will encourage applications for multi-center clinical trials to be conducted within an established Clinical Trial Research Network funded by one of multiple NIH Institutes and Centers. Following peer review, the IC will prioritize studies to be conducted within the established network infrastructure with cooperative oversight by the administering IC. The program will use the bi-phasic, milestone driven UG3/UH3 cooperative agreement activity code. Awards will initially support an up to 2- year milestone-driven planning and start-up phase, with possible transition to an implementation (UH3) phase of up to 5 additional years. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. For additional information, potential applicants are encouraged to contact program staff listed below.